Reply To: Why Outlook 2010 is Directly Opening in Safe Mode? Michael Scofield ~ Modified: January 14th, 2016 ~ ~ 1 Minute Reading Home › Forums › Why Outlook 2010 is Directly Opening in Safe Mode? › Reply To: Why Outlook 2010 is Directly Opening in Safe Mode? January 14, 2016 at 11:49 am #1040 Score: 0 Michael ScofieldModerator Karma: 20 pts Hi, In MS Outlook this issue comes due to a new December update KB3114409. Just uninstall this add-in to fix the issue. I hope it will work for you. Search